Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

Limited knowledge is available on the relationship between antigen-specific immune responses and COVID-19 disease severity. We completed a combined examination of all three branches of adaptive immunity at the level of SARS-CoV-2-specific CD4(+) and CD8(+) T cell and neutralizing antibody responses...

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Publicado no:Cell
Main Authors: Rydyznski Moderbacher, Carolyn, Ramirez, Sydney I., Dan, Jennifer M., Grifoni, Alba, Hastie, Kathryn M., Weiskopf, Daniela, Belanger, Simon, Abbott, Robert K., Kim, Christina, Choi, Jinyong, Kato, Yu, Crotty, Eleanor G., Kim, Cheryl, Rawlings, Stephen A., Mateus, Jose, Tse, Long Ping Victor, Frazier, April, Baric, Ralph, Peters, Bjoern, Greenbaum, Jason, Ollmann Saphire, Erica, Smith, Davey M., Sette, Alessandro, Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494270/
https://ncbi.nlm.nih.gov/pubmed/33010815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.09.038
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