Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of immunodominance of different SARS-CoV-2 antigens, and precisely measure virus-specific CD4 (+) and CD8 (+) T cells, we studied epitope-specific T cell responses of approximately 100 convalescent COVID-19 cases. The...

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Bibliographic Details
Published in:bioRxiv
Main Authors: Tarke, Alison, Sidney, John, Kidd, Conner K, Dan, Jennifer M., Ramirez, Sydney I., Yu, Esther Dawen, Mateus, Jose, da Silva Antunes, Ricardo, Moore, Erin, Rubiro, Paul, Methot, Nils, Phillips, Elizabeth, Mallal, Simon, Frazier, April, Rawlings, Stephen A., Greenbaum, Jason A., Peters, Bjoern, Smith, Davey M., Crotty, Shane, Weiskopf, Daniela, Grifoni, Alba, Sette, Alessandro
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743077/
https://ncbi.nlm.nih.gov/pubmed/33330869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.08.416750
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