Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of immunodominance of different SARS-CoV-2 antigens, and precisely measure virus-specific CD4 (+) and CD8 (+) T cells, we studied epitope-specific T cell responses of approximately 100 convalescent COVID-19 cases. The...

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Vydáno v:bioRxiv
Hlavní autoři: Tarke, Alison, Sidney, John, Kidd, Conner K, Dan, Jennifer M., Ramirez, Sydney I., Yu, Esther Dawen, Mateus, Jose, da Silva Antunes, Ricardo, Moore, Erin, Rubiro, Paul, Methot, Nils, Phillips, Elizabeth, Mallal, Simon, Frazier, April, Rawlings, Stephen A., Greenbaum, Jason A., Peters, Bjoern, Smith, Davey M., Crotty, Shane, Weiskopf, Daniela, Grifoni, Alba, Sette, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743077/
https://ncbi.nlm.nih.gov/pubmed/33330869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.08.416750
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