Impact of SARS-CoV-2 variants on the total CD4(+) and CD8(+) T cell reactivity in infected or vaccinated individuals

The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the importance of addressing whether the total CD4(+) and CD8(+) T cell recognition is also affected. Here, we compare SARS-CoV-2-specific CD4(+) and CD8(+) T cells against the B.1.1.7, B.1.351, P.1, and CAL.20C lineages...

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Publicado no:Cell Rep Med
Main Authors: Tarke, Alison, Sidney, John, Methot, Nils, Yu, Esther Dawen, Zhang, Yun, Dan, Jennifer M., Goodwin, Benjamin, Rubiro, Paul, Sutherland, Aaron, Wang, Eric, Frazier, April, Ramirez, Sydney I., Rawlings, Stephen A., Smith, Davey M., da Silva Antunes, Ricardo, Peters, Bjoern, Scheuermann, Richard H., Weiskopf, Daniela, Crotty, Shane, Grifoni, Alba, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249675/
https://ncbi.nlm.nih.gov/pubmed/34230917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100355
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