Negligible impact of SARS-CoV-2 variants on CD4(+) and CD8(+) T cell reactivity in COVID-19 exposed donors and vaccinees.

The emergence of SARS-CoV-2 variants highlighted the need to better understand adaptive immune responses to this virus. It is important to address whether also CD4+ and CD8+ T cell responses are affected, because of the role they play in disease resolution and modulation of COVID-19 disease severity...

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Udgivet i:bioRxiv
Main Authors: Tarke, Alison, Sidney, John, Methot, Nils, Zhang, Yun, Dan, Jennifer M., Goodwin, Benjamin, Rubiro, Paul, Sutherland, Aaron, da Silva Antunes, Ricardo, Frazier, April, Rawlings, Stephen A., Smith, Davey M., Peters, Bjoern, Scheuermann, Richard H., Weiskopf, Daniela, Crotty, Shane, Grifoni, Alba, Sette, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941626/
https://ncbi.nlm.nih.gov/pubmed/33688655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.27.433180
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