Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of immunodominance of different SARS-CoV-2 antigens and precisely measure virus-specific CD4(+) and CD8(+) T cells, we study epitope-specific T cell responses of 99 convalescent coronavirus disease 2019 (COVID-19) cas...

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Udgivet i:Cell Rep Med
Main Authors: Tarke, Alison, Sidney, John, Kidd, Conner K., Dan, Jennifer M., Ramirez, Sydney I., Yu, Esther Dawen, Mateus, Jose, da Silva Antunes, Ricardo, Moore, Erin, Rubiro, Paul, Methot, Nils, Phillips, Elizabeth, Mallal, Simon, Frazier, April, Rawlings, Stephen A., Greenbaum, Jason A., Peters, Bjoern, Smith, Davey M., Crotty, Shane, Weiskopf, Daniela, Grifoni, Alba, Sette, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837622/
https://ncbi.nlm.nih.gov/pubmed/33521695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100204
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