Impact of SARS-CoV-2 variants on the total CD4(+) and CD8(+) T cell reactivity in infected or vaccinated individuals

The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the importance of addressing whether the total CD4(+) and CD8(+) T cell recognition is also affected. Here, we compare SARS-CoV-2-specific CD4(+) and CD8(+) T cells against the B.1.1.7, B.1.351, P.1, and CAL.20C lineages...

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Bibliografiske detaljer
Udgivet i:Cell Rep Med
Main Authors: Tarke, Alison, Sidney, John, Methot, Nils, Yu, Esther Dawen, Zhang, Yun, Dan, Jennifer M., Goodwin, Benjamin, Rubiro, Paul, Sutherland, Aaron, Wang, Eric, Frazier, April, Ramirez, Sydney I., Rawlings, Stephen A., Smith, Davey M., da Silva Antunes, Ricardo, Peters, Bjoern, Scheuermann, Richard H., Weiskopf, Daniela, Crotty, Shane, Grifoni, Alba, Sette, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249675/
https://ncbi.nlm.nih.gov/pubmed/34230917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100355
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