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Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M(1) Muscarinic Acetylcholine Receptors
Positive allosteric modulators (PAMs) that target the M(1) muscarinic acetylcholine (ACh) receptor (M(1) mAChR) are potential treatments for cognitive deficits in conditions such as Alzheimer disease and schizophrenia. We recently reported novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one M(1...
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| Wydane w: | Mol Pharmacol |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616191/ https://ncbi.nlm.nih.gov/pubmed/29691279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.111633 |
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