Probing the binding site of novel selective positive allosteric modulators at the M(1) muscarinic acetylcholine receptor

Subtype-selective allosteric modulation of the M(1) muscarinic acetylcholine (ACh) receptor (M(1) mAChR) is an attractive approach for the treatment of numerous disorders, including cognitive deficits. The discovery of benzyl quinolone carboxylic acid, BQCA, a selective M(1) mAChR positive allosteri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Khajehali, Elham, Valant, Celine, Jörg, Manuela, Tobin, Andrew B., Conn, P. Jeffrey, Lindsley, Craig W., Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066355/
https://ncbi.nlm.nih.gov/pubmed/29777683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.05.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados