Probing the binding site of novel selective positive allosteric modulators at the M(1) muscarinic acetylcholine receptor

Subtype-selective allosteric modulation of the M(1) muscarinic acetylcholine (ACh) receptor (M(1) mAChR) is an attractive approach for the treatment of numerous disorders, including cognitive deficits. The discovery of benzyl quinolone carboxylic acid, BQCA, a selective M(1) mAChR positive allosteri...

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Detaylı Bibliyografya
Yayımlandı:Biochem Pharmacol
Asıl Yazarlar: Khajehali, Elham, Valant, Celine, Jörg, Manuela, Tobin, Andrew B., Conn, P. Jeffrey, Lindsley, Craig W., Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science 2018
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066355/
https://ncbi.nlm.nih.gov/pubmed/29777683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.05.009
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