Identification of a Novel Allosteric Site at the M(5) Muscarinic Acetylcholine Receptor

The M(5) muscarinic acetylcholine receptor (mAChR) has emerged as an exciting therapeutic target for the treatment of addiction and behavioral disorders. This has been in part due to promising preclinical studies with the M(5) mAChR selective negative allosteric modulator (NAM), ML375. The binding s...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:ACS Chem Neurosci
Autors principals: Burger, Wessel A. C., Gentry, Patrick R., Berizzi, Alice E., Vuckovic, Ziva, van der Westhuizen, Emma T., Thompson, Geoff, Yeasmin, Mahmuda, Lindsley, Craig W., Sexton, Patrick M., Langmead, Christopher J., Tobin, Andrew B., Christopoulos, Arthur, Valant, Celine, Thal, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616173/
https://ncbi.nlm.nih.gov/pubmed/34351123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.1c00383
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars