Laddar...

TRF2-independent chromosome end protection during pluripotency

Mammalian telomeres protect chromosome ends from aberrant DNA repair(1). TRF2, a component of the telomere-specific Shelterin protein complex, facilitates end protection through sequestration of the terminal telomere repeat sequence within a lariat t-loop structure(2,3). Deleting Trf2 in somatic cel...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Ruis, Phil, Van Ly, David, Borel, Valerie, Kafer, Georgia R., McCarthy, Afshan, Howell, Steven, Blassberg, Robert, Snijders, Ambrosius P., Briscoe, James, Niakan, Kathy K., Marzec, Paulina, Cesare, Anthony J., Boulton, Simon J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614352/
https://ncbi.nlm.nih.gov/pubmed/33239783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2960-y
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!