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CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle
Telomere end-protection by the shelterin complex prevents DNA damage signalling and promiscuous repair at chromosome ends. Evidence suggests that the 3’ single-stranded telomere end can assemble into a lasso-like t-loop configuration(1,2), which has been proposed to safeguard chromosome ends from be...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nature |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874499/ https://ncbi.nlm.nih.gov/pubmed/31723267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1744-8 |
| Ετικέτες: |
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