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CDK Substrate Phosphorylation and Ordering the Cell Cycle

S phase and mitotic onset are brought about by the action of multiple different cyclin-CDK complexes. However, it has been suggested that changes in the total level of CDK kinase activity, rather than substrate specificity, drive the temporal ordering of S phase and mitosis. Here, we present a phosp...

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Pubblicato in:Cell
Autori principali: Swaffer, Matthew P., Jones, Andrew W., Flynn, Helen R., Snijders, Ambrosius P., Nurse, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161751/
https://ncbi.nlm.nih.gov/pubmed/27984725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.034
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