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PP2A(Cdc55) Phosphatase Imposes Ordered Cell-Cycle Phosphorylation by Opposing Threonine Phosphorylation

In the quantitative model of cell-cycle control, progression from G1 through S phase and into mitosis is ordered by thresholds of increasing cyclin-dependent kinase (Cdk) activity. How such thresholds are read out by substrates that respond with the correct phosphorylation timing is not known. Here,...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Godfrey, Molly, Touati, Sandra A., Kataria, Meghna, Jones, Andrew, Snijders, Ambrosius P., Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296252/
https://ncbi.nlm.nih.gov/pubmed/28132839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.12.018
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