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Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase
Exit from mitosis in budding yeast is triggered by activation of the key mitotic phosphatase Cdc14. At anaphase onset, the protease separase and Zds1 promote the downregulation of PP2A(Cdc55) phosphatase, which facilitates Cdk1-dependent phosphorylation of Net1 and provides the first wave of Cdc14 a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854864/ https://ncbi.nlm.nih.gov/pubmed/24339788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003966 |
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