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Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase

Exit from mitosis in budding yeast is triggered by activation of the key mitotic phosphatase Cdc14. At anaphase onset, the protease separase and Zds1 promote the downregulation of PP2A(Cdc55) phosphatase, which facilitates Cdk1-dependent phosphorylation of Net1 and provides the first wave of Cdc14 a...

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Hlavní autoři: Baro, Barbara, Rodriguez-Rodriguez, Jose-Antonio, Calabria, Ines, Hernáez, María Luisa, Gil, Concha, Queralt, Ethel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854864/
https://ncbi.nlm.nih.gov/pubmed/24339788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003966
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