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Cdk-counteracting phosphatases unlock mitotic exit

Entry into mitosis of the eukaryotic cell cycle is driven by rising cyclin-dependent kinase (Cdk) activity. During exit from mitosis, Cdk activity must again decline. Cdk downregulation by itself, however, is not able to guide mitotic exit, if not a phosphatase reverses mitotic Cdk phosphorylation e...

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Hlavní autoři: Queralt, Ethel, Uhlmann, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605245/
https://ncbi.nlm.nih.gov/pubmed/18845253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.09.003
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