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Nur1 Dephosphorylation Confers Positive Feedback to Mitotic Exit Phosphatase Activation in Budding Yeast

Substrate dephosphorylation by the cyclin-dependent kinase (Cdk)-opposing phosphatase, Cdc14, is vital for many events during budding yeast mitotic exit. Cdc14 is sequestered in the nucleolus through inhibitory binding to Net1, from which it is released in anaphase following Net1 phosphorylation. In...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Godfrey, Molly, Kuilman, Thomas, Uhlmann, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287440/
https://ncbi.nlm.nih.gov/pubmed/25569132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004907
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