The end protection problem—an unexpected twist in the tail

by Ruis, Phil, Boulton, Simon J.
Published in Genes Dev (2021)

General amino acid control in fission yeast is regulated by a nonconserved transcription factor, with functions analogous to Gcn4/Atf4

by Duncan, Caia D. S., Rodríguez-López, María, Ruis, Phil, Bähler, Jürg, Mata, Juan
Published in Proc Natl Acad Sci U S A (2018)

RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions

by Kotsantis, Panagiotis, Segura-Bayona, Sandra, Margalef, Pol, Marzec, Paulina, Ruis, Phil, Hewitt, Graeme, Bellelli, Roberto, Patel, Harshil, Goldstone, Robert, Poetsch, Anna R., Boulton, Simon J.
Published in Cell Rep (2020)

CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle

by Sarek, Grzegorz, Kotsantis, Panagiotis, Ruis, Phil, Van Ly, David, Margalef, Pol, Borel, Valerie, Zheng, Xiao-Feng, Flynn, Helen R., Snijders, Ambrosius P., Chowdhury, Dipanjan, Cesare, Anthony J., Boulton, Simon J.
Published in Nature (2019)

TRF2-independent chromosome end protection during pluripotency

by Ruis, Phil, Van Ly, David, Borel, Valerie, Kafer, Georgia R., McCarthy, Afshan, Howell, Steven, Blassberg, Robert, Snijders, Ambrosius P., Briscoe, James, Niakan, Kathy K., Marzec, Paulina, Cesare, Anthony J., Boulton, Simon J.
Published in Nature (2021)

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

by Hewitt, Graeme, Borel, Valerie, Segura-Bayona, Sandra, Takaki, Tohru, Ruis, Phil, Bellelli, Roberto, Lehmann, Laura C., Sommerova, Lucia, Vancevska, Aleksandra, Tomas-Loba, Antonia, Zhu, Kang, Cooper, Christopher, Fugger, Kasper, Patel, Harshil, Goldstone, Robert, Schneider-Luftman, Deborah, Herbert, Ellie, Stamp, Gordon, Brough, Rachel, Pettitt, Stephen, Lord, Christopher J., West, Stephen C., Ahel, Ivan, Ahel, Dragana, Chapman, J. Ross, Deindl, Sebastian, Boulton, Simon J.
Published in Mol Cell (2021)