Carregant...

The end protection problem—an unexpected twist in the tail

In this perspective, we introduce shelterin and the mechanisms of ATM activation and NHEJ at telomeres, before discussing the following questions: How are t-loops proposed to protect chromosome ends and what is the evidence for this model? Can other models explain how TRF2 mediates end protection? C...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Ruis, Phil, Boulton, Simon J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778267/
https://ncbi.nlm.nih.gov/pubmed/33361389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.344044.120
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!