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Community guidelines for GPCR ligand bias: IUPHAR review 32
GPCRs modulate a plethora of physiological processes and mediate the effects of one‐third of FDA‐approved drugs. Depending on which ligand activates a receptor, it can engage different intracellular transducers. This ‘biased signalling’ paradigm requires that we now characterize physiological signal...
Kaydedildi:
| Yayımlandı: | Br J Pharmacol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2022
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612872/ https://ncbi.nlm.nih.gov/pubmed/35106752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15811 |
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