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Pharmacogenomics of GPCR Drug Targets
Natural genetic variation in the human genome is a cause of individual differences in responses to medications and is an underappreciated burden on public health. Although 108 G-protein-coupled receptors (GPCRs) are the targets of 475 (∼34%) Food and Drug Administration (FDA)-approved drugs and acco...
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| Publié dans: | Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cell Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766829/ https://ncbi.nlm.nih.gov/pubmed/29249361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.033 |
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