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Trends in GPCR drug discovery: new agents, targets and indications

G protein-coupled receptors (GPCRs) are the most intensively studied drug targets, largely due to their substantial involvement in human pathophysiology and their pharmacological tractability. Here, we report the first analysis of all GPCR drugs and agents in clinical trials. This reveals the curren...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Hauser, Alexander S., Attwood, Misty M., Rask-Andersen, Mathias, Schiöth, Helgi B., Gloriam, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882681/
https://ncbi.nlm.nih.gov/pubmed/29075003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.178
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