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Trends in GPCR drug discovery: new agents, targets and indications

G protein-coupled receptors (GPCRs) are the most intensively studied drug targets, largely due to their substantial involvement in human pathophysiology and their pharmacological tractability. Here, we report the first analysis of all GPCR drugs and agents in clinical trials. This reveals the curren...

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Détails bibliographiques
Publié dans:Nat Rev Drug Discov
Auteurs principaux: Hauser, Alexander S., Attwood, Misty M., Rask-Andersen, Mathias, Schiöth, Helgi B., Gloriam, David E.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882681/
https://ncbi.nlm.nih.gov/pubmed/29075003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.178
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