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Minireview: Targeting GPCR Activated ERK Pathways for Drug Discovery

It has become clear in recent years that multiple signal transduction pathways are employed upon GPCR activation. One of the major cellular effectors activated by GPCRs is extracellular signal-regulated kinase (ERK). Both G-protein and β-arrestin mediated signaling pathways can lead to ERK activatio...

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Detalhes bibliográficos
Main Authors: Eishingdrelo, Haifeng, Kongsamut, Sathapana
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854659/
https://ncbi.nlm.nih.gov/pubmed/24396730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501307010009
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