Minireview: GPCR and G Proteins: Drug Efficacy and Activation in Live Cells

Many biochemical pathways are driven by G protein-coupled receptors, cell surface proteins that convert the binding of extracellular chemical, sensory, and mechanical stimuli into cellular signals. Their interaction with various ligands triggers receptor activation that typically couples to and acti...

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Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Vilardaga, Jean-Pierre, Bünemann, Moritz, Feinstein, Timothy N., Lambert, Nevin, Nikolaev, Viacheslav O., Engelhardt, Stefan, Lohse, Martin J., Hoffmann, Carsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2009
Soggetti:
Special Features
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419261/
https://ncbi.nlm.nih.gov/pubmed/19196832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0204
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