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Minireview: GPCR and G Proteins: Drug Efficacy and Activation in Live Cells

Many biochemical pathways are driven by G protein-coupled receptors, cell surface proteins that convert the binding of extracellular chemical, sensory, and mechanical stimuli into cellular signals. Their interaction with various ligands triggers receptor activation that typically couples to and acti...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Vilardaga, Jean-Pierre, Bünemann, Moritz, Feinstein, Timothy N., Lambert, Nevin, Nikolaev, Viacheslav O., Engelhardt, Stefan, Lohse, Martin J., Hoffmann, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419261/
https://ncbi.nlm.nih.gov/pubmed/19196832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0204
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