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Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex
G protein-coupled receptors (GPCRs) participate in ubiquitous transmembrane signal transduction processes by activating heterotrimeric G proteins. In the current “canonical” model of GPCR signaling, arrestins terminate receptor signaling by impairing receptor–G-protein coupling and promoting recepto...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557057/ https://ncbi.nlm.nih.gov/pubmed/23297229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205756110 |
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