Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex

G protein-coupled receptors (GPCRs) participate in ubiquitous transmembrane signal transduction processes by activating heterotrimeric G proteins. In the current “canonical” model of GPCR signaling, arrestins terminate receptor signaling by impairing receptor–G-protein coupling and promoting recepto...

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Bibliografske podrobnosti
Main Authors: Wehbi, Vanessa L., Stevenson, Hilary P., Feinstein, Timothy N., Calero, Guillermo, Romero, Guillermo, Vilardaga, Jean-Pierre
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557057/
https://ncbi.nlm.nih.gov/pubmed/23297229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205756110
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