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Non-canonical signaling of the PTH receptor

The classical model of arrestin-mediated desensitization of cell-surface G protein-coupled receptors (GPCRs) is thought to be universal. However, this paradigm is incompatible with recent reports that the parathyroid hormone (PTH) receptor (PTHR), a crucial GPCR for bone and mineral ion metabolism,...

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Detalles Bibliográficos
Main Authors: Vilardaga, Jean-Pierre, Gardella, Thomas J., Wehbi, Vanessa L., Feinstein, Timothy N.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428041/
https://ncbi.nlm.nih.gov/pubmed/22709554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.05.004
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