Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium ions. It is unclear how its two native hormones, vasopressin (VP) and oxytocin (OT), both stimulate the same cAMP/PKA pathway yet produce diverge...

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Detalhes bibliográficos
Main Authors: Feinstein, Timothy N., Yui, Naofumi, Webber, Matthew J., Wehbi, Vanessa L., Stevenson, Hilary P., King, J. Darwin, Hallows, Kenneth R., Brown, Dennis, Bouley, Richard, Vilardaga, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784700/
https://ncbi.nlm.nih.gov/pubmed/23935101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445098
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