Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium ions. It is unclear how its two native hormones, vasopressin (VP) and oxytocin (OT), both stimulate the same cAMP/PKA pathway yet produce diverge...

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Main Authors: Feinstein, Timothy N., Yui, Naofumi, Webber, Matthew J., Wehbi, Vanessa L., Stevenson, Hilary P., King, J. Darwin, Hallows, Kenneth R., Brown, Dennis, Bouley, Richard, Vilardaga, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784700/
https://ncbi.nlm.nih.gov/pubmed/23935101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445098
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