Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium ions. It is unclear how its two native hormones, vasopressin (VP) and oxytocin (OT), both stimulate the same cAMP/PKA pathway yet produce diverge...

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Hlavní autoři: Feinstein, Timothy N., Yui, Naofumi, Webber, Matthew J., Wehbi, Vanessa L., Stevenson, Hilary P., King, J. Darwin, Hallows, Kenneth R., Brown, Dennis, Bouley, Richard, Vilardaga, Jean-Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784700/
https://ncbi.nlm.nih.gov/pubmed/23935101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445098
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