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Real-time optical recording of β(1)-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol
Antagonists of β-adrenergic receptors (β-ARs) have become a main therapeutic regimen for the treatment of heart failure even though the mechanisms of their beneficial effects are still poorly understood. Here, we used fluorescent resonance energy transfer–based (FRET-based) approaches to directly mo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751291/ https://ncbi.nlm.nih.gov/pubmed/17200720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30012 |
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