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Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling
The signal transduction by G Protein-Coupled Receptors (GPCRs) is mediated by heterotrimeric G proteins composed from one of the 16 Gα subunits and the inseparable Gβγ complex assembled from a repertoire of 5 Gβ and 12 Gγ subunits. However, the functional role of compositional diversity in Gβγ compl...
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| Publicado no: | Cell Syst |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068604/ https://ncbi.nlm.nih.gov/pubmed/33667409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2021.02.001 |
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