HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

CCCTC-binding factor (CTCF)-mediated stable topologically associating domains (TADs) play a critical role in constraining interactions of DNA elements that are located in neighboring TADs. CTCF plays an important role in regulating the spatial and temporal expression of HOX genes that control embryo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Luo, Huacheng, Sobh, Amin, Vulpe, Christopher D., Brewer, Edmond, Dovat, Sinisa, Qiu, Yi, Huang, Suming
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607627/
https://ncbi.nlm.nih.gov/pubmed/30985763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59382
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker