AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation

Despite being the frontline therapy for type 2 diabetes, the mechanisms of action of the biguanide drug metformin are still being discovered. In particular, the detailed molecular interplays between the AMPK and the mTORC1 pathway in the hepatic benefits of metformin are still ill defined. Metformin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Van Nostrand, Jeanine L., Hellberg, Kristina, Luo, En-Ching, Van Nostrand, Eric L., Dayn, Alina, Yu, Jingting, Shokhirev, Maxim N., Dayn, Yelena, Yeo, Gene W., Shaw, Reuben J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528705/
https://ncbi.nlm.nih.gov/pubmed/32912901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339895.120
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker