AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes

Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...

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Библиографические подробности
Опубликовано в: :Genes Dev
Главные авторы: Young, Nathan P., Kamireddy, Anwesh, Van Nostrand, Jeanine L., Eichner, Lillian J., Shokhirev, Maxim Nikolaievich, Dayn, Yelena, Shaw, Reuben J.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782048/
https://ncbi.nlm.nih.gov/pubmed/26944679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.274142.115
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