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Exercise activates lysosomal function in the brain through AMPK‐SIRT1‐TFEB pathway
AIM: To study the effects of exercise on lysosomal functions. METHODS: Mouse exercise model was established and wheel running was scheduled as 18 rpm (14:00‐17:00), 5 d/wk, for 8 weeks. Mice were injected EX527 to inhibit SIRT1 activity. The protein level was assayed with Western blot and immunofluo...
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| Publicado no: | CNS Neurosci Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6515701/ https://ncbi.nlm.nih.gov/pubmed/30864262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13114 |
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