High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://ncbi.nlm.nih.gov/pubmed/32320319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0520
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