High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://ncbi.nlm.nih.gov/pubmed/32320319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0520
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