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High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://ncbi.nlm.nih.gov/pubmed/32320319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0520
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