High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://ncbi.nlm.nih.gov/pubmed/32320319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0520
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