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High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Bibliografski detalji
Izdano u:Mol Biol Cell
Glavni autori: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://ncbi.nlm.nih.gov/pubmed/32320319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0520
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