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The nucleus is irreversibly shaped by motion of cell boundaries in cancer and non-cancer cells
Actomyosin stress fibers impinge on the nucleus and can exert compressive forces on it. These compressive forces have been proposed to elongate nuclei in fibroblasts, and lead to abnormally shaped nuclei in cancer cells. In these models, the elongated or flattened nuclear shape is proposed to store...
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| 出版年: | J Cell Physiol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673577/ https://ncbi.nlm.nih.gov/pubmed/28542912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26031 |
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