Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

The nucleus has a smooth, regular appearance in normal cells, and its shape is greatly altered in human pathologies. Yet, how the cell establishes nuclear shape is not well understood. We imaged the dynamics of nuclear shaping in NIH3T3 fibroblasts. Nuclei translated toward the substratum and began...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Li, Yuan, Lovett, David, Zhang, Qiao, Neelam, Srujana, Kuchibhotla, Ram Anirudh, Zhu, Ruijun, Gundersen, Gregg G., Lele, Tanmay P., Dickinson, Richard B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2015
Schlagworte:
Cell Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547341/
https://ncbi.nlm.nih.gov/pubmed/26287620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.006
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