Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

The nucleus has a smooth, regular appearance in normal cells, and its shape is greatly altered in human pathologies. Yet, how the cell establishes nuclear shape is not well understood. We imaged the dynamics of nuclear shaping in NIH3T3 fibroblasts. Nuclei translated toward the substratum and began...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Li, Yuan, Lovett, David, Zhang, Qiao, Neelam, Srujana, Kuchibhotla, Ram Anirudh, Zhu, Ruijun, Gundersen, Gregg G., Lele, Tanmay P., Dickinson, Richard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2015
Materias:
Cell Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547341/
https://ncbi.nlm.nih.gov/pubmed/26287620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.006
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