Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

The nucleus has a smooth, regular appearance in normal cells, and its shape is greatly altered in human pathologies. Yet, how the cell establishes nuclear shape is not well understood. We imaged the dynamics of nuclear shaping in NIH3T3 fibroblasts. Nuclei translated toward the substratum and began...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Li, Yuan, Lovett, David, Zhang, Qiao, Neelam, Srujana, Kuchibhotla, Ram Anirudh, Zhu, Ruijun, Gundersen, Gregg G., Lele, Tanmay P., Dickinson, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547341/
https://ncbi.nlm.nih.gov/pubmed/26287620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.006
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