Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

The nucleus has a smooth, regular appearance in normal cells, and its shape is greatly altered in human pathologies. Yet, how the cell establishes nuclear shape is not well understood. We imaged the dynamics of nuclear shaping in NIH3T3 fibroblasts. Nuclei translated toward the substratum and began...

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Библиографические подробности
Опубликовано в: :Biophys J
Главные авторы: Li, Yuan, Lovett, David, Zhang, Qiao, Neelam, Srujana, Kuchibhotla, Ram Anirudh, Zhu, Ruijun, Gundersen, Gregg G., Lele, Tanmay P., Dickinson, Richard B.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2015
Предметы:
Cell Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547341/
https://ncbi.nlm.nih.gov/pubmed/26287620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.006
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