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Nuclear size changes caused by local motion of cell boundaries unfold the nuclear lamina and dilate chromatin and intranuclear bodies

The mechanisms by which mammalian nuclear shape and size are established in cells, and become abnormal in disease states are not understood. Here, we tracked motile cells that underwent systematic changes in cell morphology as they moved from 1-D to 2-D micro-patterned adhesive domains. Motion of th...

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Detalles Bibliográficos
Publicado en:Soft Matter
Main Authors: Katiyar, Aditya, Tocco, VJ, Li, Yuan, Aggarwal, Varun, Tamashunas, Andrew, Dickinson, Richard B., Lele, Tanmay P.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6870954/
https://ncbi.nlm.nih.gov/pubmed/31674621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sm01666j
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