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Local, transient tensile stress on the nuclear membrane causes membrane rupture
Cancer cell migration through narrow constrictions generates compressive stresses on the nucleus that deform it and cause rupture of nuclear membranes. Nuclear membrane rupture allows uncontrolled exchange between nuclear and cytoplasmic contents. Local tensile stresses can also cause nuclear deform...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589786/ https://ncbi.nlm.nih.gov/pubmed/30566037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-09-0604 |
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