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Local, transient tensile stress on the nuclear membrane causes membrane rupture

Cancer cell migration through narrow constrictions generates compressive stresses on the nucleus that deform it and cause rupture of nuclear membranes. Nuclear membrane rupture allows uncontrolled exchange between nuclear and cytoplasmic contents. Local tensile stresses can also cause nuclear deform...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Biol Cell
Egile Nagusiak: Zhang, Qiao, Tamashunas, Andrew C., Agrawal, Ashutosh, Torbati, Mehdi, Katiyar, Aditya, Dickinson, Richard B., Lammerding, Jan, Lele, Tanmay P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589786/
https://ncbi.nlm.nih.gov/pubmed/30566037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-09-0604
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