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Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium

In search of novel protease inhibitors with therapeutic potential, our efforts exploring the marine cyanobacterium Lyngbya sp. have led to the discovery of tasiamide F (1), which is an analogue of tasiamide B (2). The structure was elucidated using a combination of NMR spectroscopy and mass spectrom...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Al-Awadhi, Fatma H., Ratnayake, Ranjala, Paul, Valerie J., Luesch, Hendrik
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957937/
https://ncbi.nlm.nih.gov/pubmed/27211244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.04.062
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