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Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium

In search of novel protease inhibitors with therapeutic potential, our efforts exploring the marine cyanobacterium Lyngbya sp. have led to the discovery of tasiamide F (1), which is an analogue of tasiamide B (2). The structure was elucidated using a combination of NMR spectroscopy and mass spectrom...

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Bibliografiska uppgifter
I publikationen:Bioorg Med Chem
Huvudupphovsmän: Al-Awadhi, Fatma H., Ratnayake, Ranjala, Paul, Valerie J., Luesch, Hendrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957937/
https://ncbi.nlm.nih.gov/pubmed/27211244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.04.062
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