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Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer

Three new 3-amino-6-hydroxy-2-piperidone (Ahp)-containing cyclic depsipeptides named loggerpeptins A–C (1–3) along with molassamide (4) were discovered from a marine cyanobacterium, extending the structural diversity of this prevalent scaffold of cyanobacterial serine protease inhibitors. Molassamid...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Al-Awadhi, Fatma H., Paul, Valerie J., Luesch, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366850/
https://ncbi.nlm.nih.gov/pubmed/29405541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700627
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