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Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer

Three new 3-amino-6-hydroxy-2-piperidone (Ahp)-containing cyclic depsipeptides named loggerpeptins A–C (1–3) along with molassamide (4) were discovered from a marine cyanobacterium, extending the structural diversity of this prevalent scaffold of cyanobacterial serine protease inhibitors. Molassamid...

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Bibliographische Detailangaben
Veröffentlicht in:Chembiochem
Hauptverfasser: Al-Awadhi, Fatma H., Paul, Valerie J., Luesch, Hendrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366850/
https://ncbi.nlm.nih.gov/pubmed/29405541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700627
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