Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor

Antzeko izenburuak

• Discovery of a Potent, Selective and Cell-active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6
  nork: Shen, Yudao, et al.
  Argitaratua: (2016)
• A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6
  nork: Shen, Yudao, et al.
  Argitaratua: (2021)
• Discovery of a Dual PRMT5–PRMT7 Inhibitor
  nork: Smil, David, et al.
  Argitaratua: (2015)
• LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity
  nork: Bonday, Zahid Q., et al.
  Argitaratua: (2018)
• Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)
  nork: Kaniskan, H. Ümit, et al.
  Argitaratua: (2017)